NORMAL INDIVIDUALS HAVE INTACT AND FUNCTIONING AUTOREACTIVE B AND T CELLS.• 70

Autoreactive T and B Cells from Bullous

Autoreactive T cells in healthy individuals.

The presence of autoreactive CD4(+) T cells in the peripheral blood of healthy human subjects was investigated after removal of CD4(+)CD25(+) regulatory T cells (Treg). CD4(+) T cells that were directed against the type 1 diabetes-associated autoantigen glutamic acid decarboxylase 65, the melanocyte differentiation Ag tyrosinase, and the cancer/testis tumor Ag NY-ESO-1 were readily derived from...

Patients Recognize Autoreactive T and B Cells from Bullous

Adult Thymus: A Forgotten Jail for Autoreactive T Cells

Autoreactive T Cells B 1 Cells Promote Pancreas